Author

Pragnya Chakraborty

Great Ormond Street HospitalORCID 0000-0002-5916-5534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

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Aditi Aggarwal· 1 shared Afrin Bhattacharya· 1 shared Ai TianiD· 1 shared Guoria Sun· 1 shared Haruka NishimuraiD· 1 shared Julien MuffatiD· 1 shared Lu‐Yang WangiD· 1 shared Luis F. ParadaiD· 1 shared

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2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aditi Aggarwal

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1 paper

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedFeb 12, 2026

ARP2/3 complex mediates the neuropathology of PTEN-deficient human neural cells downstream of mTORC1 and mTORC2 hyperactivation

Navroop K. Dhaliwal, Octavia Yifang Weng, Ai Tian…·Yun Li

This study identifies the ARP2/3 complex as a downstream effector of mTORC1 and mTORC2 hyperactivation in PTEN-deficient neural cells, showing its inhibition can rescue disease phenotypes.

1 citation

humanexperimental assay

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