Author

Haruka Nishimura

University of TorontoORCID 0000-0002-8544-3200Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aditi Aggarwal· 1 shared Afrin Bhattacharya· 1 shared Ai TianiD· 1 shared Alexander Leong· 1 shared Anson SathaseevaniD· 1 shared Bin YuiD· 1 shared Chien-Hui Chang· 1 shared Claudia Makhanko-Tang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Aditi Aggarwal

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2 papers

Recent·Most cited

ARP2/3 complex mediates the neuropathology of PTEN-deficient human neural cells downstream of mTORC1 and mTORC2 hyperactivation

Navroop K. Dhaliwal, Octavia Yifang Weng, Ai Tian, Aditi Aggarwal, Mai Essam Ahmed, Guoria Sun, Afrin Bhattacharya, Wendy W. Y. Choi, Haruka Nishimura, Pragnya Chakraborty, Xiaoxue Dong, Yuncheng Wu, Michael D. Wilson, Lu‐Yang Wang, Luis F. Parada, , Yun Li

This study identifies the ARP2/3 complex as a downstream effector of mTORC1 and mTORC2 hyperactivation in PTEN-deficient neural cells, showing its inhibition can rescue disease phenotypes.

Proceedings of the National Academy of Sciences · Feb 12, 2026Peer-reviewedNeuroscience

A stress-dependent postembryonic role for the core CPA factor CFIM-1 in germline integrity

Anson Sathaseevan, Rhea Ahluwalia, Bin Yu, Claudia Makhanko-Tang, Chien-Hui Chang, Haruka Nishimura, Alexander Leong, Ka Nam Naomi Kwan, W. Brent Derry

This study identifies a stress-dependent role for the CPA factor CFIM-1 in maintaining germline integrity in C. elegans by regulating transcript isoform abundance.

Genetics · Jan 29, 2026Peer-reviewedDevelopmental Biology