Author

Caitlin C. Winkler

University of Colorado AnschutzORCID 0000-0002-5947-5989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Santos J. FrancoiD· 3 shared Luuli N. TraniD· 2 shared Rebecca O’RourkeiD· 2 shared Bruce AppeliD· 1 shared Christina A. Kearns· 1 shared Christina N. ComoiD· 1 shared Danae N. Mitchell· 1 shared David S. LorberbaumiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Santos J. FrancoORCID

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Author profile →

4 papers

Recent·Most cited

Meningeal-derived retinoic acid regulates neurogenesis via suppression of Notch and Sox2

Christina N. Como, Rebecca O’Rourke, Caitlin C. Winkler, Danae N. Mitchell, Luuli N. Tran, David S. Lorberbaum, Lori Sussel, Santos J. Franco, Julie A. Siegenthaler

This study identifies meningeal-derived retinoic acid's role in suppressing Notch and Sox2 to regulate neurogenesis in neocortical progenitors.

Cell Reports · Apr 29, 2025Peer-reviewedNeuroscience

Temporal single-cell transcriptomes of zebrafish spinal cord pMN progenitors reveal distinct neuronal and glial progenitor populations

Kayt Scott, Rebecca O’Rourke, Caitlin C. Winkler, Christina A. Kearns, Bruce Appel

The paper uses single-cell RNA sequencing to identify two distinct progenitor populations in zebrafish spinal cord pMN cells, one producing neurons and the other producing oligodendrocytes, marked by gsx2 expression.

Developmental Biology · Jul 23, 2021Peer-reviewedDevelopmental Biology

Unraveling the transcriptional networks that drive oligodendrocyte fate specification in Sonic hedgehog-responsive neocortical progenitors

Caitlin C. Winkler, Luuli N. Tran, Ellyn P. Milan, Fernando García‐Moreno, Santos J. Franco

The paper identifies a pre-OPC state and a gene regulatory network involving Ascl1 that drives oligodendrocyte fate specification in Shh-responsive neocortical progenitors.

bioRxiv · Oct 18, 2020 · PreprintDevelopmental Biology

Loss of Shh signaling in the neocortex reveals heterogeneous cell recovery responses from distinct oligodendrocyte populations

Caitlin C. Winkler, Santos J. Franco

The paper shows that loss of Shh signaling in dorsal progenitors leads to oligodendrocyte depletion, which recovers through differential contributions from dorsal and ventral lineages, with gray matter OPCs failing to recover.

Developmental Biology · May 6, 2019Peer-reviewedNeuroscience