NeurosciencebioRxivPreprint
Blockade of VCAM1 or VLA4 preserves cerebrovasculature and prevents cognitive decline late after stroke
Kristy A. Zera, Karen P. Bradshaw, Li Zhu…·Marion S. Buckwalter
This study shows that blocking VCAM1 or VLA4 after stroke preserves vascular integrity and prevents cognitive decline by promoting blood vessel growth and restoring the blood-brain barrier.