Author

Hanadie Yousef

Stanford Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Cell Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Benoit LehallieriD· 4 shared Davis P. Lee· 4 shared Tony Wyss‐CorayiD· 4 shared Nicholas Schaum· 3 shared Daniela Berdnik· 2 shared Michelle B. Chen· 2 shared Stephen R. QuakeiD· 2 shared Aaron Demers· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersNeuroscience

Benoit LehallierORCID

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Author profile →

5 papers

Recent·Most cited

Blockade of VCAM1 or VLA4 preserves cerebrovasculature and prevents cognitive decline late after stroke

Kristy A. Zera, Karen P. Bradshaw, Li Zhu, Oliver Hahn, Aulden G. Foltz, Todd C. Peterson, Hanadie Yousef, Davis P. Lee, Elizabeth W. Mayne, Nima Aghaeepour, Tony Wyss‐Coray, Marion S. Buckwalter

This study shows that blocking VCAM1 or VLA4 after stroke preserves vascular integrity and prevents cognitive decline by promoting blood vessel growth and restoring the blood-brain barrier.

bioRxiv · Jun 25, 2025 · PreprintNeuroscience

Undulating changes in human plasma proteome across lifespan are linked to disease

Benoit Lehallier, David Gate, Nicholas Schaum, Tibor Nánási, Song Eun Lee, Hanadie Yousef, Patricia Morán Losada, Daniela Berdnik, Andreas Keller, Joe Verghese, Sanish Sathyan, Claudio Franceschi, Sofiya Milman, Nir Barzilai, Tony Wyss‐Coray

Profiling 2,925 plasma proteins in 4,331 people aged 18-95 reveals non-linear aging: protein waves crest at 34, 60 and 78 years, later waves overlapping disease proteomes.

Nature Medicine · Dec 1, 2019Peer-reviewedSystems Biology✦ In-depth digest

Brain endothelial cells are exquisite sensors of age-related circulatory cues

Michelle B. Chen, Andrew C. Yang, Hanadie Yousef, Davis P. Lee, Winnie Chen, Nicholas Schaum, Benoit Lehallier, Stephen R. Quake, Tony Wyss‐Coray

This study uses single-cell RNA sequencing to show that brain endothelial cells respond to circulatory cues of aging, with aged plasma inducing aging transcriptomes and young plasma reversing them.

Cell Reports · Jan 1, 2019Peer-reviewedNeuroscience

Single-cell transcriptomic characterization of 20 organs and tissues from individual mice creates a Tabula Muris

Nicholas Schaum, Jim Karkanias, Norma F Neff, Andrew P. May, Stephen R. Quake, Tony Wyss-Coray, Spyros Darmanis, Joshua Batson, Olga Botvinnik, Michelle B. Chen, Steven Chen, Foad Green, Robert Jones, Ashley Maynard, Lolita Penland, , Tony Wyss-Coray

The paper creates a single-cell transcriptomic atlas of 20 mouse organs and tissues, providing a resource for studying gene expression across cell types.

bioRxiv · Mar 29, 2018 · PreprintCell Biology

Aged blood inhibits hippocampal neurogenesis and activates microglia through VCAM1 at the blood-brain barrier

Hanadie Yousef, Cathrin J. Czupalla, Davis P. Lee, Ashley Burke, Michelle Chen, Judith Zandstra, Elisabeth Berber, Benoit Lehallier, Vidhu Mathur, Ramesh V. Nair, Liana N. Bonanno, Taylor Merkel, Markus Schwaninger, Stephen R. Quake, Eugene C. Butcher, Tony Wyss‐Coray

This study shows aged blood reduces hippocampal neurogenesis and activates microglia via VCAM1 at the BBB, and blocking VCAM1 reverses these effects.

bioRxiv · Jan 3, 2018 · PreprintNeuroscience