Author

Kishore Madhamanchi

University of Alabama at BirminghamORCID 0000-0002-5968-5177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Girish Chandra MelkaniiD· 2 shared Archana YadaviD· 1 shared Jianhua ZhangiD· 1 shared John C Watson· 1 shared John Watson· 1 shared Josh Kramer· 1 shared Morgan Barkley· 1 shared Srinath Gurrala· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Girish Chandra MelkaniORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 22, 2026

Microbiome Integrity Protects Against Glial-Mediated Tau and Amyloid Pathology Through Circadian and Autophagy Homeostasis

Kishore Madhamanchi, Srinath Gurrala, John Watson, Girish Chandra Melkani

This study shows that microbiome depletion worsens glial-mediated inflammation and AD-like pathology in Drosophila models by disrupting circadian rhythms, autophagy, and metabolic homeostasis.

DOI 10.64898/2026.05.20.726549

Drosophilaexperimental assay

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PhysiologyAging CellPeer-reviewedMar 1, 2026

Regulation of lipid dysmetabolism and neuroinflammation progression linked with Alzheimer's disease through modulation of Dgat2

Archana Yadav, Xiaosen Ouyang, Morgan Barkley…·Girish Chandra Melkani

This study identifies Dgat2 as a key modulator linking amyloid pathology, lipid dysregulation, and neuroinflammation in Alzheimer's disease across Drosophila and mouse models.

8 citationstop 1%

Drosophilamouse

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