Girish Chandra Melkani

This paper creates CRISPR knock-in Drosophila models of MADD with ETFDH mutations, showing exercise improves disease phenotypes.

This study shows that microbiome depletion worsens glial-mediated inflammation and AD-like pathology in Drosophila models by disrupting circadian rhythms, autophagy, and metabolic homeostasis.

This study identifies Dgat2 as a key modulator linking amyloid pathology, lipid dysregulation, and neuroinflammation in Alzheimer's disease across Drosophila and mouse models.

This paper develops an automated Drosophila locomotor assay platform integrating hardware and computer vision to improve throughput, reproducibility, and data density in locomotor behavior studies.