Andrew Macdonald

This study shows HPV E7 promotes LASP1 transcription through the Rb/E2F1 pathway in cervical cancer cells, adding to previously identified miR-203 regulation.

This study shows that HPV E7 represses miR-203, leading to LASP1 upregulation and promoting proliferation in HPV-positive cervical cancer.

This paper shows that uv-inactivated reovirus combined with sorafenib improves survival in HCC by promoting IFNβ-induced cytotoxic CD4+ T-cell responses that are MHCII-independent.

This study shows WRN regulates cell proliferation and HPV16 life cycle in epithelial differentiation by controlling DNA replication and DNA damage.

This study shows that high-risk HPV downregulates MST1, inactivating the Hippo pathway and promoting cervical cancer transformation.