Author

Emilia Kuuluvainen

University of HelsinkiORCID 0000-0003-0227-4331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:trajectory inference· 2

Frequent Co-Authors

Pekka KatajistoiD· 3 shared Jonna Saarimäki‐VireiD· 2 shared Jouni KvistiD· 2 shared Timo OtonkoskiiD· 2 shared Ville HietakangasiD· 2 shared Alessandro Ori‬‬iD· 1 shared Alexandra RitchieiD· 1 shared Anders TengholmiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersDevelopmental Biology

Pekka KatajistoORCID

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3 papers

Recent·Most cited

Metabolic commitment to human motor neurons is characterized by mitochondrial depletion and pyruvate rewiring

Rubén Torregrosa‐Muñumer, Jeremi J Turkia, Danil Spirin, Jouni Kvist, Jonna Saarimäki‐Vire, Suleva Povea-Cabello, Rumeysa Ermiş, Jana Pennonen, Emilia Kuuluvainen, Timo Otonkoski, Ville Hietakangas, Thomas G. McWilliams, Erika Fernández‐Vizarra, Pekka Katajisto, Henna Tyynismaa

The paper characterizes metabolic changes in human motor neuron differentiation, showing mitochondrial depletion and a shift in pyruvate metabolism.

bioRxiv · Oct 6, 2026 · PreprintCell Biology

Fetal-like reversion in the regenerating intestine is regulated by mesenchymal Asporin

Sharif Iqbal, Simon Andersson, Ernesta Nesta, Nalle Pentinmikko, Ashish A. Kumar, Sawan Kumar Jha, Daniel Borshagovski, Anna Webb, Nadja Gebert, Emma W Viitala, Alexandra Ritchie, Sandra Scharaw, Emilia Kuuluvainen, Hjalte List Larsen, Tuure Saarinen, , Pekka Katajisto

The paper shows that mesenchymal Asporin mediates fetal-like reprogramming in regenerating intestinal epithelium by modulating Tgfβ signaling through CD44.

Cell stem cell · Mar 6, 2025Peer-reviewedDevelopmental Biology

Functional, metabolic and transcriptional maturation of stem cell derived beta cells

Diego Balboa, Tom Barsby, Väinö Lithovius, Jonna Saarimäki‐Vire, Muhmmad Omar‐Hmeadi, Oleg Dyachok, Hossam Montaser, Per-Eric Lund, Mingyu Yang, Hazem Ibrahim, Anna Näätänen, Vikash Chandra, Helena Vihinen, Eija Jokitalo, Jouni Kvist, , Timo Otonkoski

This study generates and benchmarks functionally mature stem cell-derived islets, showing they closely resemble primary adult islets in transcriptional and functional properties.

Nature Biotechnology · Mar 3, 2022Peer-reviewedDevelopmental Biology