Author

Xiaohan Li

MRC Laboratory of Molecular BiologyORCID 0000-0002-6007-5149Unclaimed ORCID profile · follow to get notified of new preprints

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Xiaohan Li2 papers · Wenzhou-Kean University

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:long-read sequencing· 1 Approach:mechanistic / dynamical model· 1 Organism:yeast· 1

Frequent Co-Authors

Ananthanarayanan KumariD· 1 shared Conny Wing-Heng YuiD· 1 shared Elizabeth A. MilleriD· 1 shared Ellen Smith· 1 shared Fu‐Yu LiiD· 1 shared Jens JanuschkeiD· 1 shared Juan B. Rodríguez‐MolinaiD· 1 shared Lori A. PassmoreiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperMolecular Biology

Ananthanarayanan KumarORCID

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3 papers

Recent·Most cited

Bilayer thickness and transmembrane domain dynamics drive directional ER-Golgi traffic via Erv14/cornichon

Xiaohan Li, Sangram Prusty, Nicolas Loyer, María Dolores Pejenaute‐Ochoa, Niamh Riley, Ellen Smith, Jens Januschke, Qiang Cui, Elizabeth A. Miller

The paper shows that Erv14/cornichon receptor dynamics and bilayer thickness influence directional ER-Golgi traffic through a mechanism called HEIST.

bioRxiv · Aug 5, 2026 · PreprintCell Biology

Detecting Full-Length EccDNA with FLED and long-reads sequencing

Fu‐Yu Li, Wenlong Ming, Wenxiang Lu, Ying Wang, Xiaohan Li, Xianjun Dong, Yunfei Bai

The paper introduces FLED, a method combining rolling circle amplification and nanopore sequencing to detect full-length eccDNAs, identifying over 5,000 per sample in human cell lines.

Briefings in Bioinformatics · Sep 22, 2023Peer-reviewedGenomics

Dynamics in Fip1 regulate eukaryotic mRNA 3'-end processing

Ananthanarayanan Kumar, Conny Wing-Heng Yu, Juan B. Rodríguez‐Molina, Xiaohan Li, Stefan M.V. Freund, Lori A. Passmore

This study investigates the dynamics of Fip1 in the CPF complex, showing its IDR remains highly dynamic and mediates conformational transitions during mRNA 3'-end processing.

Genes & Development · Nov 1, 2021Peer-reviewedMolecular Biology