Hannes Wolfgramm

This study shows that S. aureus SplB induces asthma-like symptoms in mice, requiring proteolytic activity and adaptive immunity, suggesting a direct role of bacterial allergens in asthma.

This study uses proteomics and independent component analysis to show ClpX regulates S. aureus responses to iron and oxygen limitation and affects bacterial fitness and virulence.

This study identifies novel human substrates of Staphylococcus aureus protease SplB, revealing its cleavage of intermediate filaments and IgG, suggesting roles in immune evasion and tissue invasion.

The paper characterizes a mouse-adapted Staphylococcus aureus strain JSNZ through genomic and proteomic analysis, identifying it as a valuable reference strain for infection research.