Astrocytes amplify neurovascular coupling to sustained activation of neocortex in awake mice
Ádám Institóris, Milène Vandal, Govind Peringod, Christy Catalano, Cam Ha T. Tran, Xinzhu Yu, Frank Visser, Cheryl Breiteneder, Leonardo A. Molina, Baljit S. Khakh, Minh Dang Nguyen, Roger J. Thompson, Grant Robert Gordon
The paper shows that astrocyte Ca2+ signaling amplifies sustained functional hyperemia in awake mice, but not brief responses, through distinct mechanisms.
Nature Communications · Dec 22, 2022Peer-reviewedNeuroscience