Sefanit Rezene

This study identifies ISG expression endotypes in COVID-19 patients and links lipid metabolism to immune dysfunction in severe disease.

This study shows that ISG15-USP18 signaling limits viperin-dependent metabolic antiviral restriction by stabilizing USP18 and reducing viperin expression, thereby inhibiting viral replication.

This study uses metabolomics to compare metabolic responses to SARS-CoV-2 infection and different vaccines in ferrets, revealing distinct metabolic signatures linked to immune responses and vaccine efficacy.

This study investigates immune-coagulation dynamics in severe COVID-19 by analyzing autoantibody profiles and transcriptomics, finding correlations between autoantibody reactivities and coagulation gene expression.

This paper presents a method to simultaneously detect host and SARS-CoV-2 transcriptomes in lung tissue and identifies pathway shifts in infected cells.