Soham Gupta

This study identifies the mitochondrial transaminase GOT2 as a metabolic dependency of JEV and a potential host-directed antiviral target through integrated transcriptomics and proteomics analyses.

The paper identifies molecular signatures and endotypes in severe dengue by integrating clinical and proteomic data, revealing immune pathways associated with severe disease.

This study identifies ISG expression endotypes in COVID-19 patients and links lipid metabolism to immune dysfunction in severe disease.

This study shows that ISG15-USP18 signaling limits viperin-dependent metabolic antiviral restriction by stabilizing USP18 and reducing viperin expression, thereby inhibiting viral replication.

This study uses metabolomics to compare metabolic responses to SARS-CoV-2 infection and different vaccines in ferrets, revealing distinct metabolic signatures linked to immune responses and vaccine efficacy.

This study investigates immune-coagulation dynamics in severe COVID-19 by analyzing autoantibody profiles and transcriptomics, finding correlations between autoantibody reactivities and coagulation gene expression.

The paper identifies metabolic reprogramming in HIV-treated individuals that impairs monocyte migration and promotes M2-like macrophage polarization, enhancing HIV susceptibility.

This paper presents a method to simultaneously detect host and SARS-CoV-2 transcriptomes in lung tissue and identifies pathway shifts in infected cells.