Author

Niklas L Kahler

Karolinska Institutet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ákos VégváriiD· 1 shared Alì MirazimiiD· 1 shared Anders HoferiD· 1 shared Anoop T. AmbikaniD· 1 shared Connor BamfordiD· 1 shared Elisa SacconiD· 1 shared Éric BergeroniD· 1 shared Florine E. M. ScholteiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Ákos VégváriORCID

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1 paper

Recent·Most cited

ISG15-USP18 signaling restrains viperin-dependent metabolic antiviral restriction

Niklas L Kahler, Sefanit Rezene, Florine E. M. Scholte, Anoop T. Ambikan, Elisa Saccon, Vanessa Monteil, Prajakta Naval, Robin Macmillan, Simon Frick, Jenny Norén, Magda Lourda, Alì Mirazimi, Yenan T. Bryceson, Ronaldo Lira‐Junior, Vibhu Ranjan Prasad, , Soham Gupta

This study shows that ISG15-USP18 signaling limits viperin-dependent metabolic antiviral restriction by stabilizing USP18 and reducing viperin expression, thereby inhibiting viral replication.

bioRxiv · Mar 14, 2026 · PreprintMicrobiology