Anna Maria Langmüller

The paper uses experimental evolution to study purifying selection on P-element invasion in Drosophila simulans, finding 73% of new insertions are under purifying selection with a mean selection coefficient of -0.056.

This study investigates when spatial structure should be included in epidemiological models and derives a critical threshold for diffusion coefficient affecting disease spread predictions.

This paper develops a homing suppression gene drive in Drosophila using multiplexed gRNAs to prevent resistance alleles, achieving high conversion efficiency and moderate population suppression.

The paper compares short-term and long-term selection responses in Drosophila populations and finds low concordance between them, highlighting the need for long experiments to capture complex adaptive architectures.