De‐Li Shi

This study shows that Sirt5 protects against cardiac ischemia-reperfusion injury by inhibiting ANT2 lactylation, which enhances its interaction with VDAC1 and preserves mitochondrial function.

This study shows that N1-methylpseudouridine modification of IVT mRNA reduces dsRNA-induced translation repression and immune responses in zebrafish embryos.

The paper identifies Prkra dimer as a dsRNA sensor that blocks translation initiation in pluripotent cells, restricting viral replication and conserved across species.

The paper identifies Vrtn as a vegetally localized maternal repressor that inhibits bmp2b transcription in the marginal region, contributing to dorsoventral axis formation in zebrafish.