Author

Molly Brothers

University of California, BerkeleyORCID 0000-0002-6114-3393Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Organism:human· 1 Assay:long-read sequencing· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jasper RineiD· 2 shared Christopher T. BrowniD· 1 shared Cindy J. CastelleiD· 1 shared Cristina N. ButterfieldiD· 1 shared Daniela S. Aliaga GoltsmaniD· 1 shared David Ward TayloriD· 1 shared Dominic T. CastanzoiD· 1 shared Isabella Krudop· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Jasper RineORCID

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3 papers

Recent·Most cited

BiochemistryNature Structural & Molecular BiologyPeer-reviewedApr 13, 2026

Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency

Kaoling Guan, Rodrigo Fregoso Ocampo, Paula B. Matheus Carnevali…·David Ward Taylor

The paper compares Cas12f orthologs to identify mechanistic features that enhance genome editing efficiency in human cells.

5 citationstop 2%

humanexperimental assay

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Molecular BiologyeLifePeer-reviewedJan 24, 2022

Distinguishing between recruitment and spread of silent chromatin structures in Saccharomyces cerevisiae

Molly Brothers, Jasper Rine

The paper distinguishes between recruitment and spread of silent chromatin structures in yeast by using a fusion protein and long-read sequencing to map Sir3-chromatin interactions at single base-pair resolution.

29 citations

yeastlong-read sequencing

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GeneticsGeneticsPeer-reviewedAug 26, 2019

POL30 alleles in Saccharomyces cerevisiae reveal complexities of the cell cycle and ploidy on heterochromatin assembly

Molly Brothers, Jasper Rine

The paper investigates how POL30 alleles affect transcriptional silencing and chromatin assembly in yeast, revealing ploidy-dependent effects on genome stability.

24 citations

yeastexperimental assay

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