Author

Fang Xie

Beth Israel Deaconess Medical CenterORCID 0000-0002-6121-0875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:clinical cohort / trial· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Betul Ersoy-FazliogluiD· 2 shared David Johnson EinsteiniD· 2 shared Larysa PolubeniD· 2 shared Olga S. VoznesenskyiD· 2 shared Steven P. BalkiD· 2 shared Ada GjyreziiD· 1 shared Adam G. SowalskyiD· 1 shared Alex TokeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Betul Ersoy-FazliogluORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedFeb 14, 2026

FOXJ1 mediates taxane resistance through regulation of microtubule dynamics

Fang Xie, Ada Gjyrezi, Daniel E.C. Fein…·Steven P. Balk

This paper identifies FOXJ1 as a mediator of taxane resistance in prostate cancer by regulating microtubule dynamics, with clinical implications for patient stratification.

2 citationstop 3%

humanproteomics

Cancer BiologyJournal of Clinical InvestigationPeer-reviewedOct 2, 2025

Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion

Fen Ma, Sen Chen, Luigi Giovanni Cecchi…·Steven P. Balk

This study shows that in prostate cancer with TMPRSS2:ERG fusion, androgen deprivation increases AKT activation, which may reduce the effectiveness of AR-targeted therapy, suggesting combination therapy could be beneficial.

4 citations

mousehuman