Yifeng Cheng

In 14 rats doing probabilistic reversal learning, model-derived uncertainty (unsigned average prediction error) and recency-weighted reward history distinctly and sex-specifically shaped win-stay versus lose-shift choices.

This study shows chronic fentanyl reinforcement promotes habit formation in rats, with sex-specific effects on decision-making and perseveration during reward seeking.

This study shows that sequence termination cues, via dopamine signaling, drive habitual behavior by enhancing automaticity and reducing behavioral flexibility.

This study shows that mesostriatal dopamine responses change when specific cue-reward contingencies are altered, suggesting dopamine encodes event relationships during learning.

This study shows chronic ethanol exposure impairs cognitive flexibility and striatal decision signals in male rats, with specific changes in neural representations of actions and outcomes.

This study shows pramipexole reduces impulsivity in highly impulsive rats by modulating frontostriatal networks, specifically through Zif268 mRNA downregulation in the nucleus accumbens core.

This paper shows that drug reinforcement impairs cognitive flexibility by inhibiting striatal cholinergic interneurons through enhanced inhibitory transmission from direct-pathway medium spiny neurons.

This study shows chronic alcohol consumption impairs cognitive flexibility by reducing thalamic excitation of cholinergic neurons in the dorsomedial striatum.