Christopher Sundling

This study shows that PIM6 modulates innate immune responses in macrophages, reducing cytokine production and enhancing bacterial control during Mycobacterium tuberculosis infection.

The paper examines how prior malaria exposure reduces monocyte-driven inflammation and modulates the B cell response through changes in chemokine and BAFF levels.

The paper presents a high-resolution analysis of human IGH germline gene diversity across 2,486 individuals from 25 global populations, revealing population-specific patterns and disease-linked haplotypes.

This study identifies CD24 and CD27 as markers for tracking the differentiation of CD11c+ atypical memory B cells during malaria infection and defines their ontogeny.

This study identifies protective antibodies against Mycobacterium tuberculosis and shows that their Fc-effector function and Fab domains collaborate to restrict infection through immune cell reorganization.

This study examines IgG responses to Plasmodium falciparum MSP2, finding that naturally acquired antibodies do not target conserved termini but instead recognize variable regions and linear epitopes.

The paper analyzes NK cell subsets and function in individuals with latent TB, active TB, and healthy controls to explore their role in TB pathogenesis.

The paper introduces a genomic platform using long-read sequencing to monitor pathogen diversity and identify vaccine antigens in multiclonal infections.