Roeland M. H. Merks

This study shows laminin and fibronectin guide endothelial self-organization during intersegmental vessel formation in zebrafish by constraining network-forming behavior.

The paper shows that SOSEKI proteins respond to local mechanical and growth differences, linking tissue mechanics to polarity and axis establishment during lateral root organogenesis.

The paper compares in vitro endothelial cell network formation with three computational models to validate which model best captures the dynamics of network remodelling.

The paper investigates how environmental and competitive factors influence mutation frequencies in Streptomyces coelicolor colonies, showing that these frequencies are dynamic and responsive to the competitive environment.

The paper models cell alignment with collagen fibrils using a hybrid model showing mechanosensitive focal adhesions drive ECM-dependent cell elongation.

The paper introduces VirtualLeaf-2.0, an updated computational framework for simulating plant tissue dynamics with enhanced cell wall mechanics.

The paper uses computational simulations to show that human milk oligosaccharides (HMOs) reduce mucin consumption by promoting non-mucin-consuming bacteria over mucin-consuming ones through ecological interactions.

This study uses computational modeling to show that interdigitated structures between pacemaker and atrial cells enhance electrical pulse propagation when protrusions are of sufficient size and synchronized.

The paper uses a multiscale model to show that 2-FL supports butyrate producers in infant gut simulations by promoting propane-1,2-diol production, which outcompetes other bacteria.

This study uses gastruloids to investigate the mechanisms of elongation during gastrulation, showing that convergent extension and differential adhesion together explain the observed shape changes.

The paper develops a multiscale model of infant gut microbiota succession, showing that oxygen levels influence the transition from facultative to strict anaerobes like Bifidobacterium.

This study identifies tbx5a as essential for cardiac looping in zebrafish, showing that heart tube twisting depends on intrinsic tissue patterning and is independent of cell addition.

This study shows mechanical stretching of chicken embryos can increase vertebral numbers by inducing additional somites through cellular reorganization and mesenchymal-to-epithelial transitions.

The paper introduces MultiCellDS, a standard and community-driven initiative for sharing multicellular data to enhance research in cell biology.

The paper introduces MultiCellDS, a standard for multicellular data curation, and presents MultiCellDB as a database to store associated data, enhancing data sharing and utility in biological and clinical research.