Author

Xiangyi Li

Children's Medical CenterORCID 0000-0002-6157-8047Unclaimed ORCID profile · follow to get notified of new preprints

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Xiangyi Li1 paper · Centre National de la Recherche Scientifique

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Eliot B. BlattiD· 1 shared Feng CaiiD· 1 shared Imani M. WilliamsiD· 1 shared Islam AlshamlehiD· 1 shared Jing ZhangiD· 1 shared João S. PatrícioiD· 1 shared Jui‐Chung ChiangiD· 1 shared Lauren G. ZachariasiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Eliot B. BlattORCID

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1 paper

Recent·Most cited

BiochemistrySciencePeer-reviewedNov 6, 2025

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT

Zheng Wu, Phong T. Nguyen, Varun Sondhi…·Ralph J. DeBerardinis

This study identifies NUDT5 as a regulator of purine metabolism and thiopurine sensitivity by interacting with PPAT, independent of its known enzymatic activity.

15 citationstop 4%

humangenetic perturbation / CRISPR

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