Mònica Aguilera

This study uses single-cell RNA sequencing to map the in vivo reprogramming trajectory from acinar cells to pluripotency in the pancreas and identifies conserved intermediate markers across tissues.

This study shows that p62 is involved in Lafora body formation and that its absence reduces glycogen aggregation in muscle and heart but worsens brain pathology in a mouse model of Lafora disease.

The paper shows that GEMC1 and CCNO are essential for efferent duct development and male fertility in mice, with defects in multiciliated cell formation leading to infertility.