Author

Tiana M. Scott

Brigham Young UniversityORCID 0000-0002-6209-8301Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Ana B. Rowe· 1 shared Andrés HernándeziD· 1 shared Anne‐Sophie Jourdain· 1 shared Barbara R. PoberiD· 1 shared Boris KereniD· 1 shared Brigitte Gilbert‐DussardieriD· 1 shared Carol J. BultiD· 1 shared D. A. McCann· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Ana B. Rowe

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2 papers

Recent·Most cited

Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS

Tiana M. Scott, Lydia M. Arnold, Jordan A. Powers, D. A. McCann, Ana B. Rowe, Devin E. Christensen, Miguel J. B. Pereira, Wen Zhou, Rachel M. Torrez, Janet Iwasa, Philip J. Kranzusch, Wesley I. Sundquist, Jarrod S. Johnson

The paper shows that HIV-1 capsids protect reverse-transcribed DNA from cGAS detection, and that disrupting the capsid enhances cGAS activity.

PLoS Pathogens · Jan 28, 2025Peer-reviewedMicrobiology

Missense variants affecting the actin-binding domains of PLS3 cause X-linked congenital diaphragmatic hernia and body wall defects

Florence Petit, Mauro Longoni, Julie M. Wells, Richard S. Maser, Eric L. Bogenschutz, Matthew J. Dysart, Hannah T. M. Contreras, Frédéric Frénois, Barbara R. Pober, Robin Dawn Clark, Philip F. Giampietro, Hilger H. Ropers, Hao Hu, Marı́a Loscertales, Richard Wagner, , Frances A. High

The paper identifies missense variants in PLS3 causing X-linked congenital diaphragmatic hernia and body wall defects through genetic analysis and functional studies.

The American Journal of Human Genetics · Sep 25, 2023Peer-reviewedGenetic & Genomic Medicine