Author

Toshihide Takeuchi

Kindai University Life Science Research InstituteORCID 0000-0002-6236-8009Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Eiko Nakano MinakawaiD· 2 shared Kazuhiko SekiiD· 2 shared Yoshitaka NagaiiD· 2 shared Akihide KoyamaiD· 1 shared Akira IshiguroiD· 1 shared Akiyo Kawanobe· 1 shared Asako Murata· 1 shared Daisaku Ozawa· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Eiko Nakano MinakawaORCID

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3 papers

Recent·Most cited

NeuroscienceExperimental NeurologyPeer-reviewedOct 1, 2026

Fluid amyloid-β (Aβ) biomarkers reflect early β-sheet-rich Aβ deposition during the preclinical stage in Alzheimer's disease model 5XFAD mice

Hiroko Yagihara, 齋藤祐幸, Toshihide Takeuchi…·Eiko Nakano Minakawa

This study shows fluid amyloid-β biomarkers in 5XFAD mice correlate with β-sheet-rich Aβ deposition during preclinical Alzheimer's disease, with sex differences observed.

DOI 10.1016/j.expneurol.2026.116044

mouseproteomics

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NeurosciencebioRxivPreprintMar 12, 2025

Establishment of a second-generation transgenic marmoset model of polyglutamine disease recapitulating neurological symptoms and pathology

Eiko Nakano Minakawa, Kensuke Owari, Naotake Nogami…·Kazuhiko Seki

This paper describes a second-generation transgenic marmoset model of SCA3 that replicates motor impairments and neuropathology, offering a platform for studying disease mechanisms and therapies.

1 citation

mouseexperimental assay

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NeuroscienceeLifePeer-reviewedFeb 13, 2023

FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD

Yuzo Fujino, Morio Ueyama, Taro Ishiguro…·Yoshitaka Nagai

This study shows FUS suppresses RAN translation by modulating G-quadruplex structure of GGGGCC repeat RNA, reducing neurodegeneration in C9-ALS/FTD model flies.

20 citations

experimental assay

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