Naoki Yamanaka

This study shows that ecdysone signaling in glial cells is critical for CNS transformation during Drosophila metamorphosis, highlighting a hormone-dependent glial-neuronal interaction.

The paper identifies two cytochrome P450 epoxidases, Cyp6g2 and Cyp6a13, as essential for juvenile hormone biosynthesis in Drosophila melanogaster, showing their cooperative function and the rescue of mutant phenotypes by juvenile hormone application.

This study identifies saITP and Gyc76C as key regulators of water balance in Drosophila hindgut via a neuroendocrine axis.

The paper identifies a single prostanoid receptor in Drosophila and shows its role in tracheal development and prostanoid synthesis, highlighting a simplified eicosanoid signaling pathway compared to humans.

The paper identifies three ecdysone importers in mosquitoes and Drosophila, showing their distinct roles in development and reproduction, with EcI-2 and EcI-4 being essential in mosquitoes.

This study shows parasitic nematode fatty acid- and retinol-binding proteins (FARs) suppress host immunity by modulating lipid signaling pathways and reducing antimicrobial peptide production in flies.