Michael S. Okun

A comparative analysis of Parkinson's disease and inflammatory bowel disease gut microbiomes highlights shared depletions in key butyrate-producing bacteria

The paper compares gut microbiomes of Parkinson's disease and inflammatory bowel disease patients, finding shared depletions in butyrate-producing bacteria across multiple datasets.

Functional characterization of the biogenic amine transporter system on human macrophages

This study identifies a DAT-mediated immuno-modulatory mechanism in human macrophages, showing dopamine transport regulates innate immune responses to LPS and is disrupted in disease.

TNFα increases Tyrosine Hydroxylase expression in human monocytes

The paper develops a sensitive Bio-ELISA to measure TH in immune cells and finds that TNFα increases TH expression in monocytes from Parkinson's patients.

Synaptic processes and immune-related pathways implicated in Tourette Syndrome

This study identifies gene sets associated with Tourette Syndrome using genome-wide data, highlighting synaptic and immune-related pathways.