PhysiologybioRxivPreprint
Female Specific Restrictive Cardiomyopathy and Metabolic Dysregulation in transgenic mice expressing a Peptide of the Amino-Terminus of GRK2
Kamila M. Bledzka, Iyad H. Manaserh, Amanda Ifft…·Sarah M. Schumacher
This study shows that female mice with cardiac-restricted GRK2 amino-terminal peptide expression develop restrictive cardiomyopathy and metabolic dysregulation under pressure overload, unlike males.
DOI 10.1101/2024.10.14.618348