Sarah C. Heilshorn

This study develops a tunable DCC hydrogel platform to control viscoelastic properties for 3D human tissue modeling.

This paper introduces LINC hydrogels that use lipid mobility to control material dynamics across multiple length scales, showing that neural progenitor cells respond to nanoscale ligand dynamics.

This paper develops a hydrogel system to guide single-lumen neuroepithelial tissue formation from iPSCs, identifying matrix stress relaxation and tensional homeostasis as key regulators.

This paper develops a method to create 3D-printed collagen scaffolds with controlled fiber alignment patterns to guide cell orientation.

This paper develops a method to reinforce collagen hydrogels with bioorthogonal covalent crosslinks while preserving their fibrillar structure for tissue engineering.

This paper develops a collagen bioink for delivering corneal stem cells to wounds, promoting transparency and re-epithelialization in a rabbit model.

This study investigates how dynamic hydrogel crosslink strength affects yielding behavior and cell viability during injection, finding that slower yielding transitions enhance cell protection.

This paper introduces an interpenetrating collagen network that supports cell spreading while maintaining hydrogel stability by combining fibrillar and amorphous collagen structures.

This study shows Pf phages and sputum polymers reduce antibiotic diffusion through electrostatic binding and liquid crystal formation in chronic Pseudomonas aeruginosa infections.

This paper develops a scalable neural organoid platform using biocompatible polymers to prevent fusion, enabling drug and teratogen screening with over 2,400 cortical organoids.

The paper identifies TGFBI as a protein promoting NF-kappa-B mediated angiogenesis during early lung development by enhancing nitric oxide production.