Author

David N. Hare

Duke UniversityORCID 0000-0002-6270-3559Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Carolyn B. CoyneiD· 2 shared Kaila A CooleyiD· 1 shared Nicholas S. HeatoniD· 1 shared Rebecca L. CasazzaiD· 1 shared Samantha SkavicusiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

Carolyn B. CoyneORCID

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2 papers

Recent·Most cited

ImmunologymBioPeer-reviewedMay 5, 2026

Constitutive Interferon Epsilon Expression Shapes Antiviral Epithelial States in the Female Reproductive Tract and Intestine

Rebecca L. Casazza, Samantha Skavicus, David N. Hare…·Carolyn B. Coyne

This study identifies IFN{varepsilon} as a constitutively expressed IFN that maintains antiviral defenses in the female reproductive tract and intestine by sustaining specific epithelial states and type III IFN expression.

1 citation

mousehuman

𝕏 PostBluesky

ImmunologybioRxivPreprintApr 3, 2026

TLR3 Expression in Villus-Like Enterocytes Drives IFN-III Responses to Enteroviruses

David N. Hare, Carolyn B. Coyne

This study shows that TLR3 in villus-like enterocytes drives IFN-III responses to enteroviruses, highlighting their role in antiviral defense.

DOI 10.64898/2026.04.01.715830

humanscRNA-seq

𝕏 PostBluesky