Jarod A. Rollins

This study inserts a human RET haplotype into mice to model Hirschsprung disease, finding that regulatory variants reduce RET expression and contribute to disease.

The paper refines gene annotations in Gryllus bimaculatus using RNAseq data and identifies differentially expressed genes related to injury response and neuroplasticity.

This study shows that SOD1 trisomy disrupts ENS development and increases HSCR risk by reducing RET expression and altering glial states.

The paper shows that modified tau in C. elegans causes neuronal and global ribosome dysfunction, reducing translation and lifespan, without direct ribosome association.

The paper identifies translational repression of CYC-2.1 in the germline as a mechanism that extends lifespan through non-autonomous activation of UPRmt and AMPK in C. elegans.

This study identifies post-transcriptional mechanisms regulating longevity in C. elegans under dietary restriction, highlighting roles for RNA binding proteins, microRNA, and nonsense mediated decay.