Author

Declan F. McCole

University of California, RiversideORCID 0000-0002-6286-0802Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Charly AcevedoiD· 2 shared Aaron F. CarliniD· 1 shared Alex E. ClarkiD· 1 shared Ali ShawkiiD· 1 shared Alina N. SantosiD· 1 shared Anica Sayoc-BecerraiD· 1 shared Assael A. MadrigaliD· 1 shared Ben A. CrokeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Charly AcevedoORCID

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2 papers

Recent·Most cited

Genome-Wide Interrogation of SARS-CoV-2 RNA-Protein Interactions Uncovers Hidden Regulatory Sites

Joy S. Xiang, Karen X. Zhao, Laliv Tadri, Kurt Tamaru, Brian A. Yee, Katherine L. Rothamel, Jonathan C. Schmok, Jasmine R. Mueller, Samuel S. Park, Assael A. Madrigal, Rachael N. McVicar, Elizabeth M. Kwong, Ben A. Croker, Alex E. Clark, Aaron F. Carlin, , Gene Wei-Ming Yeo

This study maps SARS-CoV-2 protein-RNA interactions using eCLIP, revealing new regulatory sites for viral replication and translation.

Nature Communications · Oct 30, 2026Peer-reviewedMolecular Biology

Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses

Pritha Chatterjee, Marianne Rebecca Spalinger, Charly Acevedo, Alina N. Santos, Casey M. Gries, Salomon Manz, Vinicius Canale, Ali Shawki, Anica Sayoc-Becerra, Hillmin Lei, Meli’sa S. Crawford, Lars Eckmann, James Borneman, Declan F. McCole

This study shows that intestinal epithelial PTPN2 limits AIEC colonization by enhancing antimicrobial peptide expression and immune responses.

Gut Microbes · Sep 15, 2025Peer-reviewedImmunology