Author

Marianne Rebecca Spalinger

University of California, RiversideORCID 0000-0003-4498-0058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1

Frequent Co-Authors

Alessia MongelliiD· 1 shared Ali ShawkiiD· 1 shared Alina N. SantosiD· 1 shared Andrea AlimontiiD· 1 shared Anica Sayoc-BecerraiD· 1 shared Aurélien ThomasiD· 1 shared BenoÃ®t Pugin· 1 shared Casey M. GriesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Alessia MongelliORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 2, 2026

Gut Microbiota Production of Phenylacetate Programs Vascular Niche Senescence and Drives Atherosclerosis

Khatereh Shabanian, Florentin Constancias, BenoÃ®t Pugin…·Seyed Soheil Saeedi Saravi

This study identifies phenylacetate (PAA), a gut microbiota metabolite, as a driver of vascular niche senescence and atherosclerosis in mice through IL-6-Notch1 signaling.

DOI 10.64898/2026.02.27.708541

mousehuman

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ImmunologyGut MicrobesPeer-reviewedSep 15, 2025

Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses

Pritha Chatterjee, Marianne Rebecca Spalinger, Charly Acevedo…·Declan F. McCole

This study shows that intestinal epithelial PTPN2 limits AIEC colonization by enhancing antimicrobial peptide expression and immune responses.

3 citations

mouseexperimental assay

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