Author

Miwako Kakiuchi

The University of TokyoORCID 0000-0002-6300-6771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Ayumu TsubosakaiD· 2 shared Shumpei IshikawaiD· 2 shared Tetsuo UshikuiD· 2 shared Ai Nhan Thi LeiD· 1 shared Akinori KanaiiD· 1 shared Asami Yamamoto· 1 shared Chie Uekura· 1 shared Chihiro Shiomi· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

Ayumu TsubosakaORCID

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3 papers

Recent·Most cited

TET2-mutant clonal hematopoiesis prevents T-cell exhaustion and suppresses cancer metastasis

Ai Nhan Thi Le, Manabu Fujisawa, Giacomo Campo, Yen Thi Minh Nguyen, Tran Bich Nguyen, Sakurako Suma, Yasuhito Suehara, Fumihito Miura, Hiromitsu Araki, Kenichi Makishima, Tatsuhiro Sakamoto, Mizuho Nakayama, Masanobu Oshima, Miwako Kakiuchi, Shumpei Ishikawa, , Mamiko Sakata‐Yanagimoto

The paper shows TET2-mutant clonal hematopoiesis reduces cancer metastasis by preventing T-cell exhaustion through DNA methylation changes.

bioRxiv · Mar 11, 2026 · PreprintImmunology

Muc6-expressing gastric isthmus progenitors contribute to regeneration and metaplasia supported by myeloid-mesenchymal interactions

Junya Arai, Yusuke Iwata, Ayumu Tsubosaka, Hiroto Kinoshita, Shintaro Shinohara, Sohei Abe, Toshiro Shiokawa, Katsuyuki Oura, Nobumi Suzuki, Masahiro Hata, Ken Kurokawa, Yukiko Oya, Mayo Tsuboi, Sozaburo Ihara, Keita Murakami, , Mitsuhiro Fujishiro

This study identifies Muc6-expressing isthmus progenitors as key contributors to gastric regeneration and metaplasia through myeloid-mesenchymal interactions.

bioRxiv · Apr 15, 2025 · PreprintCell Biology

Single-Cell Transcriptome Analyses Reveal the Cell Diversity and Developmental Features of Human Gastric and Metaplastic Mucosa

Ayumu Tsubosaka, Daisuke Komura, Miwako Kakiuchi, Hiroto Katoh, Takumi Onoyama, Asami Yamamoto, Hiroyuki Abé, Yasuyuki Seto, Tetsuo Ushiku, Shumpei Ishikawa

This study uses single-cell RNA sequencing to create a large cell atlas of the human stomach, revealing new insights into cell diversity and developmental features, including potential stem cell markers and fibroblast distribution patterns in gastric and metaplastic mucosa.

Cell Reports · Oct 1, 2023Peer-reviewedGenomics