Author

Masanobu Oshima

Kanazawa UniversityORCID 0000-0002-3304-0004Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Masanobu Oshima1 paper

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

Ai Nhan Thi LeiD· 1 shared Alexander TyakhtiD· 1 shared Atsushi EnomotoiD· 1 shared Atsushi MasamuneiD· 1 shared Chihiro KamijoiD· 1 shared Chizu Tanikawa· 1 shared Fujiko Sueishi· 1 shared Fumihito MiuraiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Ai Nhan Thi LeORCID

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2 papers

Recent·Most cited

Co-targeting an AMPK--MAPK axis reprograms CAFs and suppresses PDAC

Ryodai Yamamura, Yusuke Satoh, Junki Fukuda, Taku Kimura, Takuya Otsuka, Sho Sekiya, Taiga Hirata, Soichiro Hata, Reo Sato, Chihiro Kamijo, Takuya Moriguchi, Shinya Kosuge, Takuya Kato, Yuya Urano, Kanako C. Hatanaka, , Masahiro Sonoshita

This study shows that targeting the AMPK-MAPK axis in cancer-associated fibroblasts suppresses PDAC growth in fly and mouse models by restoring AMPK activity and inhibiting fibroblast activation.

bioRxiv · Mar 18, 2026 · PreprintCancer Biology

TET2-mutant clonal hematopoiesis prevents T-cell exhaustion and suppresses cancer metastasis

Ai Nhan Thi Le, Manabu Fujisawa, Giacomo Campo, Yen Thi Minh Nguyen, Tran Bich Nguyen, Sakurako Suma, Yasuhito Suehara, Fumihito Miura, Hiromitsu Araki, Kenichi Makishima, Tatsuhiro Sakamoto, Mizuho Nakayama, Masanobu Oshima, Miwako Kakiuchi, Shumpei Ishikawa, , Mamiko Sakata‐Yanagimoto

The paper shows TET2-mutant clonal hematopoiesis reduces cancer metastasis by preventing T-cell exhaustion through DNA methylation changes.

bioRxiv · Mar 11, 2026 · PreprintImmunology