Capturing the onset of PRC2-mediated repressive domain formation
Ozgur Oksuz, Varun K. Narendra, Chul‐Hwan Lee, Nicolas Descostes, Gary LeRoy, Ramya Raviram, Lili M. Blumenberg, Kelly R. Karch, Pedro P. Rocha, Benjamin Aaron Garcia, Jane A. Skok, Danny Reinberg
The paper demonstrates a two-step mechanism of PRC2-mediated repressive domain formation through nucleation sites and long-range spreading of H3K27me2/3.
Molecular Cell · Jun 1, 2018Peer-reviewedGenomics