Mangal Prakash

The paper identifies ZYX-1/zyxin as a key protein linking actomyosin networks to cell-cell junctions during apical constriction in C. elegans gastrulation.

The paper investigates how extracellular matrix properties influence nuclear shape, organization, and cell fate in embryonic midline sutures through physical and genetic analyses.

The paper shows mechanical forces reduce endocardial cell volume during zebrafish cardiac valve formation through TRPP2/TRPV4 channels and hyaluronic acid.

The paper shows that during insect gastrulation, regionalized tissue fluidization by an actomyosin cable enables epithelial gap closure through cell intercalation and tension release.