Author

Rohan Misra

Albert Einstein College of MedicineORCID 0000-0002-6355-2764Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Deyou ZhengiD· 3 shared Alexander FerrenaiD· 1 shared Alexander Martinez‐FundichelyiD· 1 shared Alexander Noor ShoushtariiD· 1 shared Alexander PolyzosiD· 1 shared Andrew RosowicziD· 1 shared Christina Liu· 1 shared Christina S. LeslieiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBioinformatics

Deyou ZhengORCID

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3 papers

Recent·Most cited

shinyUMAP: an online tool for promoting understanding of single cell omics data visualization

Rohan Misra, Kevin O’Leary, Wenna Chen, Deyou Zheng

shinyUMAP is an online tool that allows users to upload single cell data and interactively generate UMAPs with different parameters to better understand cell cluster relationships.

bioRxiv · Aug 27, 2025 · PreprintBioinformatics

Facilitate integrated analysis of single cell multiomic data by binarizing gene expression values

Rohan Misra, Alexander Ferrena, Deyou Zheng

This paper shows that binarizing scRNA-seq data and integrating it with scATAC-seq data using TF-IDF and LSI improves clustering for multiomic analysis.

Nature Communications · Jul 1, 2025Peer-reviewedBioinformatics

TAD hierarchy restricts poised LTR activation and loss of TAD hierarchy promotes LTR co-option in cancer

Elissa W.P. Wong, Merve Şahin, Rui Yang, UkJin Lee, Dan Li, Yingqian Ada Zhan, Rohan Misra, Fanny V. Tomas, Nawaf Alomran, Alexander Polyzos, Cindy J. Lee, Tuan Trieu, Alexander Martinez‐Fundichely, Thomas Wiesner, Andrew Rosowicz, , Ping Chi

The paper shows that TAD hierarchy restricts LTR activation, and its loss in cancer allows LTRs to act as alternative promoters, driving oncogene activation and transcriptional diversity.

Nature Genetics · Jun 30, 2025Peer-reviewedCancer Biology