Joseph Atherton

This study uses cryo-EM to reveal drebrin's structural interaction with F-actin through two domains, explaining its modulatory role in actin networks and competitive binding with other proteins.

This study uses cryo-EM to reveal how microtubule association induces an Mg-free apo-like ADP pre-release conformation in kinesin-1, independent of tail interactions.

This study investigates SNX9's membrane binding and actin polymerization roles, finding it binds preferentially to PI(4,5)P2 and PI(3)P and forms diverse actin structures.

The paper presents a pipeline for cryo-EM image processing of microtubules using RELION, enabling accurate determination of microtubule architecture and seam location with near-atomic resolution.