Author

Lorenzo Petrolli

University of TrentoORCID 0000-0002-6392-0096Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Approach:mechanistic / dynamical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Raffaello PotestioiD· 3 shared Manuel MicheloniiD· 2 shared Alessandro PoliiD· 1 shared Alessio ZippoiD· 1 shared Chiara Bernardis· 1 shared Claudia TestiiD· 1 shared Daniela MichelattiiD· 1 shared David GenevièveiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiophysics

Raffaello PotestioORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Chromatin condensates tune nuclear mechano-sensing in Kabuki Syndrome by constraining cGAS activation

Sarah D’Annunzio, Martina Di Santo, Giulia Vitali, Lucia Santomaso, Daniela Michelatti, Leonardo Morelli, Chiara Bernardis, Maulana Ariefai, Shiza Nasir, Sara Lago, Lorenzo Lunelli, Claudia Testi, Emanuele Pontecorvo, Alessandro Poli, Fabrizio A. Pennacchio, , Alessio Zippo

The paper shows that chromatin condensates, regulated by MLL4, modulate nuclear mechano-sensing and prevent cGAS-STING activation in Kabuki Syndrome.

The EMBO Journal · Aug 12, 2026Peer-reviewedMolecular Biology

Dynamical insights on the role of supercoiling on DNA radiosensitivity

Manuel Micheloni, Raffaello Potestio, Lorenzo Petrolli

The paper uses molecular dynamics simulations to study how supercoiling affects DNA radiosensitivity, finding that negative supercoiling increases rupture likelihood under specific conditions.

Physics in Medicine and Biology · Mar 19, 2026Peer-reviewedBiophysics

Sequence and supercoiling-dependent effects on the structural dynamics of DNA minicircles

Manuel Micheloni, Luca Tubiana, Raffaello Potestio, Lorenzo Petrolli

The paper uses molecular dynamics simulations to study how DNA sequence and superhelical density affect structural dynamics in minicircles, finding that undercoiling leads to stable denaturation bubbles.

Biophysical Reports · Oct 31, 2025Peer-reviewedBiophysics