Author

Lorenzo Lunelli

Fondazione Bruno KesslerORCID 0000-0002-8824-2084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alessandra PisciottaniiD· 1 shared Alessandro PoliiD· 1 shared Alessandro ProvenzaniiD· 1 shared Alessandro QuattroneiD· 1 shared Alessio ZippoiD· 1 shared Aurora BadaloniiD· 1 shared Cecilia PerrucciiD· 1 shared Chiara Bernardis· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Alessandra PisciottaniORCID

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2 papers

Recent·Most cited

Molecular BiologyThe EMBO JournalPeer-reviewedAug 12, 2026

Chromatin condensates tune nuclear mechano-sensing in Kabuki Syndrome by constraining cGAS activation

Sarah D’Annunzio, Martina Di Santo, Giulia Vitali…·Alessio Zippo

The paper shows that chromatin condensates, regulated by MLL4, modulate nuclear mechano-sensing and prevent cGAS-STING activation in Kabuki Syndrome.

DOI 10.1038/s44318-026-00884-z

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Molecular BiologybioRxivPreprintMay 15, 2025

Disruption of ribosome dynamics and mRNA homeostasis triggers a cascading imbalance in protein synthesis in models of Amyotrophic Lateral Sclerosis

Fabio Lauria, Federica Maniscalco, Cecilia Perrucci…·Gabriella Viero

This study investigates how TDP-43 dysregulation disrupts protein synthesis in ALS models by altering ribosome dynamics and mRNA homeostasis, revealing a conserved mechanism across in vitro and in vivo systems.

DOI 10.1101/2025.05.15.654227

humanproteomics

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