Mingxi Huang

GDBIG: the first birth cohort genomic database and platform facilitating intergenerational genetic research

GDBIG provides a genomic database and platform for intergenerational genetic research using data from the Born in Guangzhou Cohort Study.

Utilizing Non-Invasive Prenatal Test Sequencing Data Resource for Human Genetic Investigation

The paper develops methods for analyzing low-depth NIPT sequencing data to accurately estimate allele frequencies and genetic effect sizes, enabling population genetic studies.

Genetic study of intrahepatic cholestasis of pregnancy in 101,023 Chinese women unveils East Asian-specific etiology linked to historic HBV infection

This study identifies East Asian-specific genetic loci for intrahepatic cholestasis of pregnancy linked to historical HBV infection, using genome-wide association analyses in 101,023 Chinese women.

Genome-wide association and Mendelian randomisation analysis among 30,699 Chinese pregnant women identifies novel genetic and molecular risk factors for gestational diabetes and glycaemic traits

This study identifies four genetic loci associated with gestational diabetes risk and 31 loci linked to glycaemic traits in 30,699 Chinese pregnant women, with MTNR1B showing the strongest association.

Large-scale Inference of Population Structure in Presence of Missingness using PCA

EMU accurately infers population structure from ultra-low coverage sequencing data with missingness, outperforming existing methods on real and simulated datasets.