Abigail Kalmbach

Striatal pathways oppositely shift cortical activity along the decision axis

The paper investigates how direct and indirect basal ganglia pathways influence cortical activity during decision-making, finding that they oppositely modulate a subset of neurons encoding decision variables.

A multisensory circuit for gating intense aversive experiences

This paper identifies a novel vCA1[->]pPVN circuit that modulates both learned and innate fear by regulating neuronal activity in the PAG.

Substantia nigra dopamine neurons evoke a delayed excitation in lateral dorsal striatal cholinergic interneurons via glutamate cotransmission

The paper shows that SN dopamine neurons use different receptors in different dStr subregions to send distinct signals to cholinergic interneurons and spiny projection neurons.

Dopamine neuron dependent behaviors mediated by glutamate cotransmission

This study shows that reducing glutamate cotransmission in dopamine neurons affects amphetamine sensitization and latent inhibition, contributing to schizophrenia resilience.