Stephen Rayport

Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration

This study identifies VGLUT-mediated mechanisms protecting DA neurons from PD-related degeneration, revealing sex-specific effects and transcriptional regulators.

Single dose of amphetamine induces delayed subregional attenuation of striatal cholinergic interneuron activity

This study maps the delayed effects of a single amphetamine dose on striatal cholinergic interneuron activity using p-rpS6 imaging in mice, showing subregional attenuation after 24 hours.

Dopamine neuron synaptic connectivity defines physiological striatal domains

The paper maps dopamine neuron synaptic actions across striatal regions, revealing regional heterogeneity and physiological domains.

Substantia nigra dopamine neurons evoke a delayed excitation in lateral dorsal striatal cholinergic interneurons via glutamate cotransmission

The paper shows that SN dopamine neurons use different receptors in different dStr subregions to send distinct signals to cholinergic interneurons and spiny projection neurons.

Dopamine neuron dependent behaviors mediated by glutamate cotransmission

This study shows that reducing glutamate cotransmission in dopamine neurons affects amphetamine sensitization and latent inhibition, contributing to schizophrenia resilience.

Skin photoreceptors in the leopard frog

The paper explores the evolutionary origins of vertebrate sense organs by examining the relationship between skin receptors and specialized sensory structures.