BiochemistryRedox BiologyPeer-reviewed
The mitochondrial Na+/Ca2+ exchanger NCLX is implied in the activation of hypoxia-inducible factors
Carmen Choya-Foces, Elisa Navarro, Cristóbal de los Rı́os…·Antonio Martı́nez-Ruiz
This study shows that NCLX is necessary for HIF-1 stabilization and transcriptional activity during hypoxia, linking acute and medium-term hypoxic responses through mitochondrial signaling.
15 citations