Antonio Martı́nez-Ruiz

This study shows sodium aurothiomalate induces ferroptosis by covalently modifying GPX4 through a gold-dependent mechanism, leading to tumor growth reduction in preclinical models.

This study shows that NCLX is necessary for HIF-1 stabilization and transcriptional activity during hypoxia, linking acute and medium-term hypoxic responses through mitochondrial signaling.