Author

Kiran Kumar

Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware, USA;ORCID 0000-0002-6467-1239Unclaimed ORCID profile · follow to get notified of new preprints

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Kiran Kumar4 papers · Broad Institute

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1

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Angela M. GronenborniD· 1 shared Barbie K. Ganser-PornillosiD· 1 shared Caitlin M. QuinniD· 1 shared Carl T. Wild· 1 shared Eric O. FreediD· 1 shared Jayden A. Martinez· 1 shared Owen PornillosiD· 1 shared Roman ZadorozhnyiiD· 1 shared

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2026-2026 · peak 1/yr

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Angela M. GronenbornORCID

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Recent·Most cited

BiophysicsbioRxivPreprintNov 6, 2026

Structural Basis of Second-Generation HIV-1 Maturation Inhibitor Activity by Magic Angle Spinning NMR

Kiran Kumar, Roman Zadorozhnyi, Timothy N. Porter…·Tatyana Polenova

This study uses MAS NMR to determine the binding mode of HRF-4467, a second-generation HIV-1 maturation inhibitor, in the CA-SP1-NC11 complex with IP6, revealing its mechanism of action and resistance profile.

DOI 10.64898/2026.11.05.764638

structural biologyexperimental assay

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