Author

Mary Elisabeth Ehmann

Massachusetts Institute of TechnologyORCID 0009-0002-3117-8293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Synthetic Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Deon S. PloessliD· 3 shared Kate E. GallowayiD· 3 shared Albert Blanch-AsensioiD· 2 shared Adam M. BeitziD· 1 shared Brittany A Lende-DorniD· 1 shared Caroline G. Brown· 1 shared Catherine Marin Della SantinaiD· 1 shared Derin R. GumustopiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersSynthetic Biology

Deon S. PloesslORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Self-amplifying RNA enables rapid, durable, integration-free programming of hiPSCs

Catherine Marin Della Santina, Deon S. Ploessl, Nicole Lindsay‐Mosher, Caroline G. Brown, Mary Elisabeth Ehmann, Albert Blanch-Asensio, Eung Chang Kim, Edward S. Boyden, Kate E. Galloway, Laurie A. Boyer

This paper demonstrates that self-amplifying RNA (saRNA) enables durable, integration-free transgene expression in hiPSCs, supporting cell-fate programming and functional reporter analysis.

Cell Reports Methods · Sep 1, 2026Peer-reviewedBioengineering

Programmable nanobody circuits for cell selection

Nathan Wang, Albert Blanch-Asensio, Hannah Cevasco, Deon S. Ploessl, Derin R. Gumustop, Mary Elisabeth Ehmann, Maria Castellanos, Francisco J. Sánchez Rivera, Timothy Mark O’Shea, Kate E. Galloway

This paper introduces DASIT, a protein-based circuit for antigen-specific cell selection, demonstrating its utility in genome engineering, CRISPR screening, and cell therapy manufacturing.

bioRxiv · Feb 23, 2026 · PreprintSynthetic Biology

Programmable promoter editing for precise control of transgene expression

Sneha R Kabaria, Yunbeen Bae, Mary Elisabeth Ehmann, Brittany A Lende-Dorn, Adam M. Beitz, Emma L. Peterman, Kasey S. Love, Deon S. Ploessl, Kate E. Galloway

DIAL is a framework for designing synthetic promoters that generate heritable, tunable gene expression setpoints across cell types.

Nature Biotechnology · Oct 13, 2025Peer-reviewedSynthetic Biology