Author

Luca Golinelli

KU LeuvenORCID 0000-0002-6484-8284Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Isabel BeetsiD· 3 shared Liesbet TemmermaniD· 2 shared ALEXANDER R. GOTTSCHALKiD· 1 shared Angela MousleyiD· 1 shared Bethany A. Crooks· 1 shared Christopher P. Wray· 1 shared Ciaran J. McCoyiD· 1 shared Erschad Bassam· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Isabel BeetsORCID

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3 papers

Recent·Most cited

Autocrine feedback maintains homeostatic neuropeptide expression in a peptidergichub neuron

Luca Golinelli, Isabel Beets, Liesbet Temmerman

The paper identifies an autocrine feedback mechanism in C. elegans AVK neurons that regulates neuropeptide expression and secretion through FLP-1 and DMSR-7 interactions.

Genetics · Oct 10, 2026Peer-reviewedNeuroscience

Exploitation of phylum-spanning omics resources reveals complexity in the nematode FLP signalling system and provides insights into flp-gene evolution

Ciaran J. McCoy, Christopher P. Wray, Laura Freeman, Bethany A. Crooks, Luca Golinelli, Nikki J. Marks, Liesbet Temmerman, Isabel Beets, Louise E. Atkinson, Angela Mousley

This study identifies 2143 flp-genes across 100+ nematode species, revealing evolutionary patterns and expression dynamics of FLPs in parasitic nematodes.

BMC Genomics · Dec 19, 2024Peer-reviewedEvolutionary Biology

Hierarchical regulation of functionally antagonistic neuropeptides expressed in a single neuron pair

Ichiro Aoki, Luca Golinelli, Eva Dunkel, Shripriya Bhat, Erschad Bassam, Isabel Beets, ALEXANDER R. GOTTSCHALK

The paper shows two neuropeptides from a single neuron pair in C. elegans have opposing effects on locomotion, with one inhibiting the release of the other through autocrine feedback.

Nature Communications · Nov 3, 2024Peer-reviewedNeuroscience